1. Patient swallow urea capsule labeled with ¹³C/¹?C.
2. If the patient is infected with H. pylori, orally administered ¹³C/¹?C-Urea will be hydrolyzed into ammonia and ¹³CO?/¹?CO?.
3. ¹³CO?/¹?CO? is absorbed into the blood circulation and exhaled by the lung.
4. Collect the pre-dose and post-dose exhale breath and analyze the variation of ¹³C/¹²C ratio in exhaled CO? to diagnose the infection of H. pylori (¹³C-Urea Breath Test) .
Collect the exhale breath and test it. The presence of a significant amount of ¹?CO? in the exhaled breath indicates active H. pylori infection (¹?C-Urea Breath Test) .